Margin control in minutes before incision closing, with histology-grade confidence.

The Histolog® Scanner is a digital microscopy scanner for ultra-fast confocal imaging of fresh excision. It reveals the morphology of the tissue at the subcellular level. In the treatment of cancer, the Histolog® Scanner can help clinicians to visualize the excision’s margins.


The Histolog Scanner® has the potential to improve my confidence and ensure complete tumor removal during breast conserving surgery.

Dr. P.-M. Genolet, Surgeon Gynaecologist, Switzerland

The Clinical Need

When surgically excising a tumor, the challenge for the surgeon is to remove all of the cancerous tissue while preserving as much as possible the healthy surrounding tissue. This is particularly true for breast conserving surgery and Mohs surgery in dermatology. To control the resection, it is specially prepared in thin slices for microscopy slide analysis in the pathology lab. The preparation of the slides takes time and it is done after the surgery. Depending on results, there may be a need to reoperate the patient for removing the remaining cancerous tissue. The patient care is improved when immediate margin assessment is made available during surgery.


The Histolog® Scanner in your clinical practice

In light of this need, SamanTree Medical teams up with surgeons and pathologists to bring confocal microscopy in the operating room. As a result, the Histolog Scanner® seamlessly integrates in the operating theater.

Once resected the full excision is simply dipped in a contrast agent and placed on a disposable dish over the imaging window. Within 1 minute the fresh excision is ready for imaging. There is no need for fixing, nor embedding, nor glass mounting of the excision. Then, within a few seconds, a digital image of the excision surface is displayed on a touch screen which allows to zoom and move around in the image. Surgeon can visualize suspicious lesion at a glance. Importantly, the excision remains intact for later final assessment.

The Histolog Scanner (v1 CE-mark, March 2016) has been used in renowned centers to demonstrate its imaging performance in both Mohs and breast cancer specimens. The upgraded Histolog Scanner® v2.0 is CE marked since October 2018 and is now available to accommodate whole lumpectomy specimens.

  • 2017 Clinical Study with Dr. C. Tausch at Brust Zentrum Zürich – Switzerland
  • 2018 Collaboration in Lausanne – Switzerland with Dr. P.-M. Genolet (breast surgeon, private gynecologist) and with Dr. L. Taminelli / Dr. M. Fiche (pathologists, Medical Laboratory)
  • 2019 Clinical Studies in Europe
  • 2016 Clinical study with Prof. Dr. M. Möhrle, dermatologist renown in Mohs surgery based in Tübingen, Germany. University of Tübingen is recognized as one of the largest dermatological cancer center in Europe, see here.
  • 2016 Collaboration with Dr. O. Gaide, from CHUV (Centre Hospitalier Universitaire Vaudois in Switzerland).

With the Histolog Scanner®, the morphology of the freshly excised tissue is immediately visualized without the need for freezing or fixing.

Contact Us

SamanTree Medical SA

Avenue de Provence 12
1007 Lausanne
Phone number: +41 21 625 09 40