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A faster and more flexible approach to Mohs and slow Mohs

Fast intra-operative assessment with no slide preparation, compatible with diverse specimens.

The clinical need

In the context of Mohs or slow Mohs surgery, frozen section analysis provides an accurate method to examine the surgical specimen. However, slide preparation takes time and requires a complex organization and workflow. The patient will have to wait for the results with an open wound for up to 24 hours before the surgery can be finalized.

Furthermore, some tumor excisions can present atypical topology or size preventing them to qualify for Mohs or slow Mohs procedures.

Needs to be met

In order to make Mohs and slow Mohs more comfortable and accessible for the patient, as well as optimize the clinical workflow, the following requirements must be met:

  • Fast intraoperative assessment

  • Imaging method compatible with diverse specimens

  • Simplified organizational procedure

Our solution

The Histolog Scanner has been designed to fit seamlessly into the surgical workflow and help surgeons to ensure complete tumor removal at primary surgery.

The open-top architecture allows clinicians to scan the margin of specimens of diverse shapes and sizes. Preparation of the specimen takes only a few seconds, and the image is available in less than a minute.


Understand how the Histolog Scanner fits into your surgical workflow.

„The Histology Scanner enables fast and accurate per-operative imaging of surgical margins in skin cancer patients. Its open-top design accommodates specimens of various shapes and sizes.”

Dr. Kuonen

Dr. F. Kuonen, Dermatologist
CHUV, Lausanne, Switzerland

Our latest published study in dermatology

Evaluation of the Histolog Scanner as an alternative for H&E in Mohs surgery

L. Grizzetti, F. Kuonen, CHUV, Switzerland
Skin Health and Disease, 2022

  • Drastic time saving

  • Basal Cell Carcinoma: Sensitivity >80% and Specificity 100%

  • The Histolog Scanner has the potential to become a new standard in Mohs surgery

Prospective study on 109 specimens

Previously published studies in dermatology

Evaluation of Histolog Scanner on giant skin surgical specimens

N. Kechrid, F. Kuonen, CHUV, Switzerland
JAAD, 2022

  • Only technique allowing scanning of giant skin surgical specimens

  • Allows direct reconstruction to maximize patient benefits

Case report on two giant BCCs


Evaluation of the process to generate and analyze CLSM images and assessment of the accuracy to detect basal cell carcinoma (BCC) tissue

N. Peters, M. Schubert, G. Metzler, J-P. Geppert, M. Moehrle, Universitätsklinikum Tübingen, Germany
Journal of the European Academy of Dermatology and Venereology, 2018

  • Time-saving and very effective alternative to the classical paraffin-embedded or frozen section

  • BCC detection performance: sensitivity >70% & specificity 96%

Prospective study on 544 fresh specimens