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Prostatectomy: Immediate evaluation of excised prostatic tissue

The Histolog Scanner delivers rapid digital imaging of the entire prostate surface within minutes right in the operating room, while enabling remote pathology review and collaboration in real time.

Explore workflow
Clinicians in scrubs looking at an image of fresh specimen on the Histolog Scanner with surgical robot in the background

5-20 minutes


vs. 45-60 min with NeuroSAFE 1

79-91% sensitivity


Demonstrated across clinical studies 1,2,3

94-100% specificity


Demonstrated across clinical studies 1,2,3

Cost effective


Intraoperative assessment during RARP 4

References

1 Baas, D.J.H., Vreuls, W., Sedelaar, J.P.M. Vrijhof, H.J.E.J. Hoekstra, R.J., Zomer, S.F, van Leenders, G.J.L.H., Jvan Basten, J.A., Somford., D.M. Confocal laser microscopy for assessment of surgical margins
during radical prostatectomy. BJU Int. Published online 2022.
https://doi:10.1111/BJU.15938

2 Almeida-Magana R., et. al. Accuracy of the LaserSAFE technique for detecting positive surgical margins during robot-assisted radical prostatectomy: blind assessment and inter-rater agreement analysis. Histopathology. 2025 Feb;86(3):433-440.
https://doi: 10.1111/his.15336

3 Mayor, N., et al., IP8-FLUORESCE: A Prospective Paired Cohort Study Evaluating the Diagnostic Accuracy of Fluorescence Confocal Microscopy for Real-time Assessment of Surgical Margins in Radical Prostatectomy. Eur Urol, 2025.
https://doi.org/10.1111/bju.16588

4van Drumpt J.N.H.1, Govers T.M., Almeida-Magana R., Baas D.J.H.1, Haider A., Sedelaar J.P.M., Shaw G., Somford D.M. (2026). Cost-effectiveness of intraoperative surgical margin assessment during radical prostatectomy. BJU International 2026 https://doi:10.1111/bju.70121

Clinical workflow
a 4-step procedure within 5 minutes

Excision

Collection of fresh tissue.

Preparation

Immerse the excision in Histolog Dip for 10 sec, and rinse it for 2 - 5 sec in saline. This process is non-destructive, requires no slicing and no slides.

Imaging

Scan the specimen surface in ~1 minute. The specimen remains visible and accessible during the entire procedure.

Evaluation

Review Histolog images immediately. This can be done on-site on the Histolog touchscreen, or remotely via Histolog Remote.

Focus on the results

Nerve on prostate

Nerve on prostate

Smooth muscle on prostate

Smooth muscle on prostate

Infiltrating glands on prostate

Infiltrating glands on prostate

Histolog Image Training

The Histolog Image Training (HIT) was developed with our community of pathologists and experts to provide a simple and efficient way of getting familiar with Histolog images. Designed for both beginners and experienced morphology content readers, the HIT allows for flexible learning.

Discover the HIT Academy

Curious about the Histolog Scanner ? Contact us.

A&P-00953 V2-International